Ultimate Guide line of Modafinil is the topic of our discussion in this article .We would try to cover a lot of aspects of modafinil in our next articles. So if you want to know some thing thing special about modafinil then stay tuned with us in future.
Overview: Ultimate Guide line of Modafinil
Modafinil is a central nervous system Stimulant. Which is mostly used in narcoleptic syndrome. Its is alpha 1 adrenergic receptor agonist .It is chemically related to adrafinil. It increases dopamine neurotransmitter effect in brain and increases tendency for wakefulness.
Indications
Modafinil is indicated in conditions which are mentioned below.
- Narcolepsy
- Sleep Apnea Syndrome/obstructive sleep apnea/hypopnea syndrome (OSAHS)
- Shift work sleep disorder (SWSD) to stay awake during the day time
- recurring sleep episodes during day time.
- sleepiness due due to shift work sleep disorder.
- Idiopathic hypersomnia.
Off label use of modafinil. It is used in following conditions:
- Acute unipolar and bipolar depressive episodes
- Cancer related fatigue
- Attention deficit hyperactivity disorder
- Multiple sclerosis related fatigue
- cocaine dependence
- Apathy in Alzheimer’s disease
- Adjunctive therapy in Schizophrenia
- chronic fatigue syndrome
Contraindications
Modafinil is contraindicated in conditions like:
- Pregnancy
- Breast Feeding
- Hypertension of pregnancy
- Hypertension with angina
- Myocardial Infarction(MI) especially Non ST-segment elevation myocardial infarction
Monitoring during Provigil (Modafinil) Use
Base line Electrocardiogram should be performed before starting modafinil. So That any harmful effects could easily be detected.
Side Effects of Modafinil
Side Effects of Modafinil have a wide range of list but we would try to list them as maximum as we can .So the list of modafinil is as below:
Note: Possible Solutions of each side effects are provided just click on the side effect.
- Headache
- Anorexia
- Anxiety
- Nausea (Feeling of vomiting)
- Palpitation (Feeling heart beat which is not felt in normal person)
- Tachycardia
- Nervousness
- Insomnia
- Abdominal pain
- Dry Mouth
- Hypertension
- Tremors
- Psychoses
- Depression
- Hallucination
- Euphoria
- CNS stimulation
- Excitation
- Personality Disturbances
- Gastric Discomfort
- Bucco-facial Dyskinesia
- Rashes
- Pruritus
- rhinitis
- diarrhea
Above all there are many other side effects of modafinil which can vary person to person.
Over Dose symptoms of Provigil
If you have taken high doses of provigil(modafinil) you may feel following symptoms:
- Confusion
- Restlessness
- Nausea
- Feeling disoriented
- Sleep disturbances
- Chest pain
- Slow or fast heart rate
- Increased blood pressure
- Feeling excited
- Diarrhea
- Hallucination
Warnings: Ultimate Guide line of Modafinil
Modafinil should be used with caution in following patients.
Hepatic Impaired Patients: Patients with chronic liver disease (CLD) should reduce the dose of modafinil to half.
Renal Impairment: Patient with renal impairment chronic Kidney disease (CKD) should reduce the dose of modafinil to half of original dose.
Hypertension Patients: Patient with hypertension should monitor their heart rate and blood pressure very closely . IF you wan to buy monitor click here.
Alcoholic Beverages and Modafinil: alcoholic beverages should be avoided with modafinil use.
Pregnancy and modafinil: During pregnancy only clearly need based utilization of modafinil is indicated after recommendation from your doctor.
Pediatrics modafinil: Modafinil is not recommended in any scenario in children’s.
High Risk Groups
Here is a list of some high risk people for the use of modafinil.
- Hypertension
- Pregnancy
- Children
- Myocardial infarction patients
- Chronic kidney disease patients
- Chronic liver disease patients
- Any scenario where risks are greater than benefits
- Allergy to any component of modafinil
Molecular Formula
Molecular formula of modafinil is C15H15NO2S.
Chemical Name
Chemical formula of modafinil is Diphenylmethyl-sulfinylacetamide.
Molar Mass
Molar Mass of modafinil is 273.35 g/mol.
Metabolism of Modafinil in our body.
Modafinil is metabolized by liver in our body. This process occurs by amide hydrolysis. So patients with liver damage should reduce the amount of it so that its dose did not increase in our body .
Protein binding of Modafinil in plasma.
Modafinil when gets into blood it is 62.3% bound to proteins in plasma.
What drug class is modafinil?
Modafinil is used to promote wakefulness. It increases some neurotransmitters in some parts of brain which increase wakefulness and inhibits sleep.
Is modafinil a smart drug?
In long run the side effects of modafinil does not make it a smart choice. In short run as Adderall and modafinil increases wakefulness so you can complete your job or study work but it is not a wise choice to use it in long run because memory storage for long term use is only occurs when we sleep on proper time and awake after deep sleep.
What does modafinil do to the brain?
Modafinil increases the amount of dopamine in our brain. Basically when two nerves are connected they form a synapses(connection) between them . which is connected to each others by chemicals called neurotransmitters like acetylcholine and dopamine. These are released and transmitted by one neuron and absorbed by other. It basically inhibits their clearance from synapsis and thus increases their time of interaction.
Manufacturer of Modafinil Drug
Above all there are many other manufacturer of modafinil.
Retailers of Modafinil
- cvs
- walgreens
- costco
- amazon
- superdrug
- walmart
Above all there are many other retailers of modafinil.
Available doses
This drug is available is following doses:
- Modafinil 200mg
- Tablet Modafinil 100mg
- Modafinil 50 mg
Route of Dose Administration of Modafinil
Once in morning by oral route . Your doctor may recommend a second dose at noon.
Dose of Modafinil for Narcolepsy
Once in the morning or may be a noon dose if directed by your doctor.
Dose of Modafinil for Obstructive Sleep Apnea
Usually once in the morning with or without food or directed by your doctor.
Dose of Modafinil for Shift Worker
As shift worker have different sleep pattern . So to avoid mishap in next shift .Recommended dose is one hour before shift work.
Should I Suddenly Stop taking Modafinil
No you should not stop taking modalert suddenly as it can cause withdrawal symptoms like nausea, chills , vomiting etc. Always consult your doctor before this. Your doctor may first reduce the dose of drug than gradually stop it.
Can Modafinil cause Addiction?
Yes it may cause addiction. The tendency for addiction is more in those people who have substance abuse disorder like drugs/ alcohols . So you should consult your doctor regarding dosage and interval for taking this medicine.
Marijuana(cannabis) and Modafinil
Use of marijuana with modafinil can make you more dizzy. So driving, machine work or any work requiring more alertness, should not be done when you use marijuana with it.
Should i tell doctor before pregnancy about use of Modafinil
yes you should tell your doctor about modalert use before conceiving for pregnancy as it can harm your baby.
Birth control and Modafinil
You should use non hormonal forms of birth control methods when you are using modafinil. As it reduces the response of hormonal birth control pills, ring and patch. So using it with hormonal birth controls is not recommended.
Breast feeding and Modafinil
Do not use modafinil with breast feeding. However You should consult your doctor for use of modalert before breast feeding to your baby.
MDM/Ecstasy , Methamphetamine and Modafinil
Modafinil interacts with methamphetamine and and MDM / ecstasy.
Modafinil increases excretion of some other drugs
It induces metabolism of some drugs so causes early removal of those drugs from body thus reducing their beneficial effects on body. These drugs are Bosutinib, axitinib, asunaprevir, ombitasvir/ritonavir/paritaprevir.
Does Modafinil increases Heart Rate and Blood Presure
yes some parts of chemical structures of modalert can increase your heart rate and blood pressure .
Caffeine and Ultimate Guide line of Modafinil
Caffeine which is the component of Tea, coffee, colas, and large amount of chocolate can increase the effects of modafinil. For instance if you take modafinil pill with cup of tea or coffee you are gonna have more side effects with early onset.
Is armodafinil same as Modafinil
yes armodafinil is same as modafinil so armodafinil can increase the effects of modefinil on your body.
Dose Modafinil causes Hallucinations
yes it causes hallucinations. So if you are having hallucination contact your health care provider.
Share Modafinil with other: Ultimate Guide line of Modafinil
Do not share it with others. It is against the law. It has addiction potency. Modafinil can harm others. So do not share it with others.
Missed dose of Modafinil
If you miss the dose of modafinil no worries take it as soon as possible. If you are near the next dose than you should miss previous dose and take next days dose. In conclusion do not take over dose of modafinil in any scenario.
Bedtime and missed dose of Modafinil
Do not take missed dose of modafinil at your bed time as it can interfere with your normal sleep. In Conclusion to have better sleep avoid it before bed time.
Storage of Modafinil
Store modafinil at room temperature. Prevent it from light and moisture. Keep it away from children. Do not store it in bathroom.
How Modafinil Affects studying?
Studies says that it does not increase long term memory. However it improves decision making and planning abilities.
Why is Provigil a controlled substance?
Provigil (modafinil) is abused. It can lead to dependence and addiction. That is why it is controlled substance.
Is Modafinil Vyvanse?
Provigil and vyvanse are brand names . Vyvanse is not available in generic form while provigil brand name is available in generic form as modafinil. So Vyvanse is modafinil.
Is Modafinil beneficial for fatigue?
Yes modafinil is beneficial for fatigue. It stimulates central nervous system. So if you fatigued modafinil can make you feel fresh.
Adderall vs Modafinil which is dangerous?
Studies says that adderall is more dangerous than modafinil. So do not use it.
Does Modafinil reduces weight?
As Modafinil reduces clozapine associated fatigue. So modafinil causes significant weight loss.
How do i get modafinil?
First of all you can not get controlled substance without prescription. Secondarily modafinil is a controlled substance . So a valid prescription from a licensed healthcare provider can get you modafinil.
How to buy modafinil?
you can go to nearby pharmacy with valid prescription. So that you can get modafinil refill.
How to buy modafinil online?
if you want to buy modafinil online you can check this article .
In Conclusion Modafinil is a controlled substance, should only be used with valid prescription, avoided in children, should not use with marijuana, used only for narcolepsy, sleep apnea syndrome, shift worker. It also concludes that it is prohibited to share it with others. It also concludes that modafinil has a lot of side effects and should use with precautions.
We hope that you would have find our article “Ultimate Guide line of Modafinil” very helpful. If you want more health related article especially arthritis click here.